Release date: 2012-12-14
Beijing time on December 13th news, according to the US Science Life Network LiveScience reported that Chinese scientists have recently invented a new method of manufacturing brain cells, this method is simpler and safer than the previous method of extracting human blood to make brain cells. The most amazing thing is that this new method actually creates new brain cells by collecting the epithelial cells in the kidneys that the body naturally excretes urine.
Making stem cells from urine Scientists use urine to extract epidermal cells to regenerate stem cells, which can become any kind of cells in the human body, including brain cells. In this study, scientists have successfully transformed these cells into nerve cells and brain cells. The latest research results of scientists have been published in the journal Nature Method on Sunday.
Perhaps in the future when the technology is widely used, doctors can quickly acquire brain cells that are critical to the patient. And because the technology relies on human urine, this technique is much simpler and safer than the original method of making brain cells by drawing patient blood. Because in this way the doctor does not need to extract any other things from the patient, it is only necessary to collect the naturally discharged urine. Mark Lalande, a researcher at the University of Connecticut Medical Center, told reporters that "for a child patient, getting their urine is much simpler than taking blood from them."
For years, scientists have been trying to experiment with different ways to transform other types of cells into stem cells. Researchers have experimented with making insulin from testicular stem cells to turn brain cells into stem cells. This method has also been used to treat Parkinson's disease and Alzheimer's disease.
Christine Brennan, a stem cell researcher at Mount Sinai School of Medicine in the United States, who did not participate in the study, said that many of the original methods used viruses to transmit new genetic information to the DNA of cells. Because viral DNA will permanently stay in the cell's genetic code, this can cause some unpredictable behavior in these cells, and even mutate the cells into tumors.
In recent research, Chinese research teams have used a more secure approach. The researchers turned brain cells into cells by collecting epidermal cells from the kidneys that were excreted in the urine and injecting new genetic instructions into them. With these new genetic instructions, the collected cells become brainstem cells, which can also be transformed into various other brain cells as needed. The entire process from kidney cells to brain stem cells takes only about 12 days. In less than half a month, new brain cells will be completely produced.
In the test results for mice, this way of using urine to make brain cells does not cause tumors to appear in cells. Since this approach is suitable for almost any patient, the research results can now be considered the most advanced method in the field.
Original link:Generation of integration-free neural progenitor cells from cells in human urine
Source: Sina Technology News
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