The use of somatic cells to clone animals is nothing new, but the current cloning process is very complex, requires expensive equipment, and the success rate is low. Danish and Australian scientists have collaborated to develop a simple and easy cloning technology that is expected to make up for deficiencies in existing technologies.
In previous cloning trials, professionals used expensive micromanipulators to insert a very fine needle into the egg under a microscope, remove the nucleus, and use another such needle to seed the somatic cell nucleus of the animal to be cloned. The entire process is complex and difficult to transplant, and it takes a long time. The new cloning technology invented by Danish and Australian scientists is to use a very thin blade to cut the egg in half under a microscope. Cut it exactly enough so that half of the nucleus is intact and the other half is only cytoplasm. The two cells, which are only half of the cytoplasm, are fused together to form an intact, enucleated egg cell structure, which is then combined with the somatic cell nucleus of the animal to be cloned. This is then split by current stimulation to produce the embryo.
The biggest advantage of this technology is that the required equipment is relatively cheap, and the technical requirements for operators are also reduced. This not only saves research expenses, but also facilitates automation. This technique has the potential to achieve large reproduction of good breeds of livestock, thus accelerating the development of clone agriculture. It is said that half of the bovine embryos produced by this method are successfully developed and can be used for transplantation, and the success rate is not lower than the current cloning technology. A calf cloned in this way has already been born in Australia and looks very healthy.
Another important use of this technology is to save endangered animals. South African scientists have successfully used this method to combine bovine eggs with the nucleus of endangered animals such as the South African white gemsbok and impala to develop healthy embryos. They also transplanted 5 cattle embryos into 3 cows. If they can produce healthy calves, the scientists will consider the next step of experimenting, that is, trying to use ordinary animals to provide eggs to their endangered relatives and act as surrogate mothers. Cloning of endangered animals.
Research on cloning technology has made rapid progress in recent years, with frequent successes. American scientists have developed cloning quails, which is not only the first time in the world that equine animals have been cloned, but also the first successful attempt to clone hybrid animals; the Chinese-French scientists used the “repair surgery†that was invented in the study of cloned mice and cloned cattle. "The invention of a patented technology that can precisely control the spontaneous activation of rat oocytes has also succeeded in obtaining cloned rats. Its success will play an important role in the development and improvement of animal development mechanisms and animal cloning technologies. To study human chronic diseases such as cancer, diabetes and hypertension. Australian researchers extracted DNA from a Tasmanian tiger wolf wolf specimen that had been preserved for 130 years and successfully replicated it, promising to reproduce the reproduction of extinct animals. Researchers at the University of Missouri developed four genetically engineered cloned pigs. One of their genes that caused rejection was removed. This experiment is a step toward the goal of using animal organs as substitutes for human organs.
In previous cloning trials, professionals used expensive micromanipulators to insert a very fine needle into the egg under a microscope, remove the nucleus, and use another such needle to seed the somatic cell nucleus of the animal to be cloned. The entire process is complex and difficult to transplant, and it takes a long time. The new cloning technology invented by Danish and Australian scientists is to use a very thin blade to cut the egg in half under a microscope. Cut it exactly enough so that half of the nucleus is intact and the other half is only cytoplasm. The two cells, which are only half of the cytoplasm, are fused together to form an intact, enucleated egg cell structure, which is then combined with the somatic cell nucleus of the animal to be cloned. This is then split by current stimulation to produce the embryo.
The biggest advantage of this technology is that the required equipment is relatively cheap, and the technical requirements for operators are also reduced. This not only saves research expenses, but also facilitates automation. This technique has the potential to achieve large reproduction of good breeds of livestock, thus accelerating the development of clone agriculture. It is said that half of the bovine embryos produced by this method are successfully developed and can be used for transplantation, and the success rate is not lower than the current cloning technology. A calf cloned in this way has already been born in Australia and looks very healthy.
Another important use of this technology is to save endangered animals. South African scientists have successfully used this method to combine bovine eggs with the nucleus of endangered animals such as the South African white gemsbok and impala to develop healthy embryos. They also transplanted 5 cattle embryos into 3 cows. If they can produce healthy calves, the scientists will consider the next step of experimenting, that is, trying to use ordinary animals to provide eggs to their endangered relatives and act as surrogate mothers. Cloning of endangered animals.
Research on cloning technology has made rapid progress in recent years, with frequent successes. American scientists have developed cloning quails, which is not only the first time in the world that equine animals have been cloned, but also the first successful attempt to clone hybrid animals; the Chinese-French scientists used the “repair surgery†that was invented in the study of cloned mice and cloned cattle. "The invention of a patented technology that can precisely control the spontaneous activation of rat oocytes has also succeeded in obtaining cloned rats. Its success will play an important role in the development and improvement of animal development mechanisms and animal cloning technologies. To study human chronic diseases such as cancer, diabetes and hypertension. Australian researchers extracted DNA from a Tasmanian tiger wolf wolf specimen that had been preserved for 130 years and successfully replicated it, promising to reproduce the reproduction of extinct animals. Researchers at the University of Missouri developed four genetically engineered cloned pigs. One of their genes that caused rejection was removed. This experiment is a step toward the goal of using animal organs as substitutes for human organs.
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