Release date: 2014-05-29
Many people suffer from Posttraumatic stress disorder in the event of a car accident or severe trauma. A new study found that a drug that treats multiple sclerosis may help alleviate this traumatic memory.
The drug, called Fingolimod, contains a small molecule that can inhibit the body's immune system, help regulate the immune system in patients with multiple sclerosis, and alleviate excessive immune system. Actively caused by a series of symptoms such as inflammation.
In a new issue of the British journal Nature Neuroscience, American researchers reported that they first discovered through animal experiments that fingolimod has a new role in which small molecules can inhibit deacetylase. This enzyme plays a role in gene expression processes related to memory and learning. Although the specific mechanism is still unclear, animal experiments have found that rats taking this drug can forget the pain more quickly.
In the experiment, the rats showed high tension and anxiety after receiving a slight electric shock, and they would not be close to the place where they were shocked for a long time. The researchers fed some experimental mice with fingolimod and repeated the experiment. It was found that the experimental rats who took the drug recovered more quickly from the traumatic shadow than the other experimental rats.
Sarah Spiegel, a senior author of the paper and the Virginia Commonwealth University in the United States, said that if this new role of fingolimod is further confirmed in human clinical trials, it is expected to bring new hope to patients with "post-traumatic stress disorder".
Source: bio360
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